Relationship between diabetic retinopathy and angiotensin converting enzyme gene deletion polymorphism: a systemic review
10.3760/cma.j.issn.1000-6699.2010.08.013
- VernacularTitle:糖尿病视网膜病变与血管紧张素转换酶基因缺失多态性的系统评价
- Author:
Yun TIAN
;
Runjuan WANG
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy;
Angiotensin converting enzyme gene
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(8):679-681
- CountryChina
- Language:Chinese
-
Abstract:
To clarify the relationship between angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and diabetic retinopathy in type 2 diabetic patients by meta analysis. 16 eligible articles were selected in this study, including 1 014 patients with diabetic retinopathy and 1 135 controls. The meta analysis revealed that systematic data Z= 2.91 ( P = 0.004 ), OR = 1.69 ( 95% CI 1.19-2.40). There is association between ACE gene I/D polymorphism and the diabetic retinopathy in type 2 diabetic patients.
