Relationship study between IL-3,IL-5 and IL-8 and Nasal polypus
10.3760/cma.j.issn.1008-6706.2010.14.037
- VernacularTitle:IL-3、IL-5及IL-8与鼻息肉的关系研究
- Author:
Wen ZHAO
- Publication Type:Journal Article
- Keywords:
Nasal polypus;
Interleukin-3;
Interleukin-5;
Interleukin-8
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(14):1944-1945
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of IL-3,IL-5 and IL-8 in the genesis and development of nasal polypus(NP) by testing IL-3 ,IL-5 and IL-8 Value in Nasal polypus issue. Methods 50 cases of nasal polyps and 30 casesof normal middle turbinate mucosa were involved in this study. Concentrations of IL-3, IL-5 and IL-8 were determined by enzyme linked immunosorbent assay(ELISA). Results The levels of IL-3 ,IL-5 and IL-8 in Nasal polypus issue were significantly higher than that in control group( P ＜ 0.05 ). Conclusion The levels of IL-3, IL-5 and IL-8 in Nasal polypus issue rised,They likely played a certain role in the genesis and development of NP.
