Contrast-enhanced ultrasound to detect hepatic artery stenosis after orthotopic liver transplantation
10.3760/cma.j.issn.1004-4477.2010.08.016
- VernacularTitle:超声造影诊断肝移植术后肝动脉狭窄
- Author:
Ren MAO
;
Jie REN
;
Rongqin ZHENG
;
Mei LIAO
;
Erjiao XU
;
Ping WANG
;
Minqiang LU
;
Yang YANG
;
Changjie CAI
;
Guihua CHEN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Liver transplantation;
Hepatic artery stenosis
- From:Chinese Journal of Ultrasonography
2010;19(8):684-687
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of contrast-enhanced ultrasound(CEUS) for detection of hepatic artery stenosis(HAS) in recipients following orthotopic liver transplantation(OLT). Methods CEUS was performed in 50 OLT recipients (42 men and 8 women) with abnormal liver function test and/or abnormal findings on color Doppler ultrasound(CDUS). Digital subtraction angiography (DSA), computed tomographic angiography(CTA) or follow-up CDUS was used as the reference standard. The degree (mild,narrowing rate＜50 %; moderate, narrowing rate 50 % ～ 75 %; severe, narrowing rate＞ 75 % ), location and type (single or multiple) of HAS were evaluated. Moderate and severe stenosis were defined as substantial stenosis. Results CTA or DSA depicted substantial HAS in 39 patients, 8 patients with mild HAS or normal HA were depicted on CTA,and the remaining 3 patients were diagnosed as non-substantial HAS on clinical and CDUS follow-up. CEUS depicted substantial HAS in 38 cases. Moreover,CEUS corrected falsepositive findings on CDUS in 9 of 50 cases(18.0% ). The accuracy, sensitivity, specificity, positive predictive value and negative predictive value of CEUS in diagnosing HAS were 90.0% ,92.3% ,81.8% ,94. 7% and 75.0%,respectively. Conclusions CEUS is able to provide comprehensive information including presence,degree,location and type of HAS, which may facilitate the further interventional procedure or surgical treatment.
