Primary study on resting myocardial perfusion in type 2 diabetes mellitus patients with real-time myocardial contrast echocardiography

Weibin LI; Qing Lü; Mingxing Xie; Lin HE; Jing Wang; Yanrong Zhang; Yuyuan Chen; Kike Duan

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Primary study on resting myocardial perfusion in type 2 diabetes mellitus patients with real-time myocardial contrast echocardiography

VernacularTitle:实时心肌超声造影评价2型糖尿病患者静息状态下心肌灌注特点的初步研究
Author: Weibin LI ; Qing Lü ; Mingxing XIE ; Lin HE ; Jing WANG ; Yanrong ZHANG ; Yuyuan CHEN ; Kike DUAN
Publication Type:Journal Article
Keywords: Echocardiography; Microbubbles; Diabetes mellitus,type 2; Myocardial perfusion
From: Chinese Journal of Ultrasonography 2010;19(8):655-658
CountryChina
Language:Chinese
Abstract: Objective To explore the characteristics of resting myocardial perfusion of type 2 diabetes mellitus(T2DM) by real-time myocardial contrast echocardiography(RT-MCE). Methods Thirteen patients with T2DM and 12 in control were enrolled in the study. RT-MCE was performed using a continuous infusion of SonoVue with vena mediana in elbow. Images of left ventricle filled with contrast were acquired from apical 4-, 2-chamber and long axis views with real-time myocardial contrast mode of GE Vivid 7 Dimension system. All above images were captured in continuous 3 cardiac cycles before "flash" ,and then 15 cardiac cycles after "flash". All clips were stored for off-line analysis. Results In quiescent condition, there were significant decrease on indices of A,k and A × k in patients compared with control group (A:6.46 ±1.60 vs 6.81 ± 1.53, P ＜0.05;k:1.04 ± 0.39 vs 1.28 ± 0.31*, P ＜0.01;A× k:6.55 ± 2.72 vs 8.78 ±3.16, P ＜ 0.01, respectively). Conclusions RT-MCE could evaluate the early change of myocardial perfusion in T2DM patients and offers important reference for clinical diagnosis and treatment.