Primary study on resting myocardial perfusion in type 2 diabetes mellitus patients with real-time myocardial contrast echocardiography
10.3760/cma.j.issn.1004-4477.2010.08.004
- VernacularTitle:实时心肌超声造影评价2型糖尿病患者静息状态下心肌灌注特点的初步研究
- Author:
Weibin LI
;
Qing Lü
;
Mingxing XIE
;
Lin HE
;
Jing WANG
;
Yanrong ZHANG
;
Yuyuan CHEN
;
Kike DUAN
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Microbubbles;
Diabetes mellitus,type 2;
Myocardial perfusion
- From:
Chinese Journal of Ultrasonography
2010;19(8):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of resting myocardial perfusion of type 2 diabetes mellitus(T2DM) by real-time myocardial contrast echocardiography(RT-MCE). Methods Thirteen patients with T2DM and 12 in control were enrolled in the study. RT-MCE was performed using a continuous infusion of SonoVue with vena mediana in elbow. Images of left ventricle filled with contrast were acquired from apical 4-, 2-chamber and long axis views with real-time myocardial contrast mode of GE Vivid 7 Dimension system. All above images were captured in continuous 3 cardiac cycles before "flash" ,and then 15 cardiac cycles after "flash". All clips were stored for off-line analysis. Results In quiescent condition, there were significant decrease on indices of A,k and A × k in patients compared with control group (A:6.46 ±1.60 vs 6.81 ± 1.53, P <0.05;k:1.04 ± 0.39 vs 1.28 ± 0.31*, P <0.01;A× k:6.55 ± 2.72 vs 8.78 ±3.16, P < 0.01, respectively). Conclusions RT-MCE could evaluate the early change of myocardial perfusion in T2DM patients and offers important reference for clinical diagnosis and treatment.