Inflnence of Benazepril combined with jinshuibao capsules on the furction of patients with lyperlensive renal disease
10.3760/cma.j.issn.1008-6706.2010.14.015
- VernacularTitle:贝那普利联合金水宝对高血压肾损害患者肾功能的影响
- Author:
Hongbo ZHANG
;
Ruili YANG
- Publication Type:Journal Article
- Keywords:
Hypertensive disease;
Kidney damage;
Urine protein;
Ccr;
Benazepril;
Jinshuibao capsules
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(14):1901-1902
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe influence of Benazepril combined with Jinshuibao capsules on urine protein and Ccr in patients hypertensive renal disease. Methods 47 hypertensive renal disease patients were randomly divided into control group and combine group. Patients in control group were treated with Benazepril, while patients in combined group were treated Jinshuibao plus Benazepril. Clinic index change after treatment for 9 weeks was observed, and calculation endogenous creatinine clearance rate was calculated. Results After treatment for 9 weeks urine protein in 24 hours of two groups were both lower than before( t1 = 1. 9997 ,t2 = 3.3088 ,P ＜ 0. 05 or P ＜ 0. 01 ),while the endogenous creatinine clearance rate were both higher than before ( t1 = 1. 3990, t2 = 1. 4442, P ＞ 0. 05 ), and the press were all in improvment ( t1 = 2.0047, t2 = 2.4557, t3 = 2.0426, t4 = 2.4026, P ＜ 0. 05 ); urine protein in 24 hours of combine group was lower than control group( t = 2.0015,P ＜ 0. 05) Conclusion Benazepril plus Jinshuibao capsules could obviously abate urine protein on patients with hypertensive disease and hypertensive renal disease
