Allotransplantation of fetus parathyroid after radiated with 60Co and cultured in nude rats
- VernacularTitle:经60钴照射及裸鼠过渡的胚胎甲状旁腺同种移植四例
- Author:
Renbin LIU
;
Guorui CHEN
- Publication Type:Journal Article
- Keywords:
Parathyroid glands;
Transplantation;
Hypoparathyroidism;
Brachytherapy
- From:
Chinese Journal of Organ Transplantation
1998;19(1):42-44
- CountryChina
- Language:Chinese
-
Abstract:
Allotransplantation with fetus parathyroids was performed in 4 cases of hypoparathyroidism after the grafts had been radiated with 6 Gy of 60Co and cultured in Balb/c nude rats for 14 davs.The recipients took 4 days of cyclosporine A(dose of 20～25mg·kg-1/d),one day preoperation and 3 days postoperation.The patients were followed up for 5～60 months.Traced observation on the patients'clinical symptoms and signs,the changes in the doses of Calcium and Vitamine D and in the levels of serum Calcium and parathyroid hormone was conducted to determine the grafts'survival.The results were satisfactory with all cases surviving for the follow-up period.It is considered that this method is much better than any we did previously.
