Dithothreitol (DTT) treating lymphocytes highly sensitized antibodies in renal pretransplantation patients
- VernacularTitle:二硫苏糖醇处理淋巴细胞毒高敏感肾移植透析患者抗体的研究
- Author:
Baoxiang JIA
;
Hong LIU
;
Yuhai ZHANG
- Publication Type:Journal Article
- Keywords:
Renal/transplantation;
Dithithreitol(DTT);
Antibody
- From:
Chinese Journal of Organ Transplantation
1997;18(2):120-122
- CountryChina
- Language:Chinese
-
Abstract:
72 sera of highly sensitized antibody patients were detected by 35 samples of undonor lymphocytes before and after the dithothreitol (DTT) treating.The results showed that 72 sera reacted completely to B lymphocytes in both 4℃ and 37℃,but incompletely to T lymphocytes.After removal of the transplant kidney due to rejection,the sera antibody levels of T or B lymphocytes were higher than those of the patients'sera after blood transfusion or pregnancy.The serum T or B antibody levels of pregnancy were the lowest.In DTT-treated sera of highly sensitized patients,the antibodies were mixed types of IgG and IgM.
