Treatment of septic shock from upper urinary obstruction

VernacularTitle:上尿路梗阻致脓毒性休克的治疗
Author: Limin YANG ; Yipeng HU ; Bing CHEN ; Jian LIU ; Yi LIU ; Zhenyu LI ; Huajie ZHAO
Publication Type:Journal Article
Keywords: Upper urinary obstruction; Septic shock; Continuous veno-venous haemofiltration
From: Chinese Journal of Urology 2010;31(8):516-519
CountryChina
Language:Chinese
Abstract: Objective To investigate the treatment of septic shock(SS) from upper urinary obstruction(UUO). Methods Continuous veno-venous haemofiltration(CVVH) combined with surgical method was applied to 42 SS patients from UUO. Their general conditions, liver and kidney functions, APACHE Ⅱ, therapeutic intervention scorisystem(TISS), multiple organ dysfunction syndrome (MODS), complication rate and main outcomes were analysed comparing with traditional therapies groups(n=30). Results Compared with those traditional therapies, the APACHEⅡ , MODS and TISS score decreased (P＜0.05). Thirty-seven out of 42 patients survived and the survival rate was 88.0% during ICU. Conclusion CVVH combined with surgical methods may effectively decrease the incidence of complications and mortality of SS from UUO, and the mechanism may be related to the remove of mediators of inflammation.