An antimicrobial resistance surveillance of gram-positive cocci isolated from 12 teaching hospitals in China in 2009
10.3760/cma.j.issn.0578-1426.2010.09.004
- VernacularTitle:2009年中国12家教学医院革兰阳性球菌耐药性研究
- Author:
Hongli SUN
;
Hui WANG
;
Minjun CHEN
;
Yingmei LIU
;
Zhidong HU
;
Kang LIAO
;
Yunzhuo CHU
;
Jine LEI
;
Bing ZHANG
;
Yunsong YU
;
Bijie HU
;
Ziyong SUN
;
Zheng ZHANG
;
Qiyong HE
- Publication Type:Journal Article
- Keywords:
Drug resistance,bacterial;
Anti-bacterial agents;
Gram-positive cocci
- From:
Chinese Journal of Internal Medicine
2010;49(9):735-740
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate antimicrobial resistance among gram-positive cocci in China in 2009. Methods From June to December 2009, 1169 consecutive and non-repetitive gram-positive cocci were collected from 12 teaching hospitals at 9 cities. The minimal inhibitory concentration (MIC) of antibacterial agents was determined by agar dilution method. Results The prevalences of methicillinresistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative Staphylococci (MRCoNS) were 45.3% (211/466) and 89. 5% (214/239), respectively. The isolation rate of MRSA was 33. 3%-68. 1% from different samples. All Staphylococci isolates were susceptible to vacomycin, teicoplanin and linezolid. Five point five percent (7/128) E. faecium strains were resistant to vacomycin. All E.faecalis strains were susceptible to vacomycin. About 99. 1% (108/109) of E. faecalis and E. faecium were susceptible to linezoild. The prevalence of penicillin-intermediate Streptococcus pneumoniae (PISP) was 21.6% (48/222). Only 1 (0. 5%, 1/222) Streptococcus pneumoniae strain was resistant to penicillin.Teicoplanin, vancomycin, linezolid and tigecycline were the most active agents against Streptococcus pneumoniae (susceptible rate 100% ). Conclusions The high prevalence of methicillin-resistance is among Staphylococcus strains. Different samples show a different MRSA prevalence. Teicoplanin, vancomycin and linezolid show very high activity to Staphylococci,E. faecalis, E. faecium and Streptococcus pneumoniae.
