Study of strain and strain rate imaging in systemic lupus erythematosus

VernacularTitle:系统性红斑狼疮患者左心功能的应变和应变率研究
Author: Hao LIANG ; Tao JIA ; Mei ZHU ; Juan FENG ; Nan ZHANG ; Zhenwei GUO ; Huijun MOU ; Ming YANG ; Wenbin GUO
Publication Type:Journal Article
Keywords: Echocardiography; Lupus erythematosus,systemic; Ventricular function,left
From: Chinese Journal of Ultrasonography 2010;19(8):666-669
CountryChina
Language:Chinese
Abstract: Objective To investigate the diagnosis value of the tissue strain imaging in myocardial dysfunction in systemic lupus erythematosus (SLE). Methods Sixty-two patients and sixty controls underwent conventional and tissue Doppler echocardiography. Peak strain and strain rate value during systolic and diastolic phases as well as E/A, left ventricular fraction shortening (LVFS), left ventricular ejection fraction(LVEF) were measured in both SLE and the control groups. Results ①E/A,LVFS and LVEF did not differ between SLE patients and controls( P ＞0.05). The systolic peak strain and strain rate of SLE patients were lower than those of controls but without significant differences( P ＞0.05). ②The diastolic peak strain and strain rate of SLE patients were significantly lower than those of controls (P ＜0.01). ③ The diastolic peak strain and strain rate of antiheart antibody (AHA) positive patients were significantly lower than those of negative ones( P ＜0.05). Conclusions Strain and strain rate combining with AHA can sensitively detect myocardial dysfunction of SLE.