Study of strain and strain rate imaging in systemic lupus erythematosus
10.3760/cma.j.issn.1004-4477.2010.08.009
- VernacularTitle:系统性红斑狼疮患者左心功能的应变和应变率研究
- Author:
Hao LIANG
;
Tao JIA
;
Mei ZHU
;
Juan FENG
;
Nan ZHANG
;
Zhenwei GUO
;
Huijun MOU
;
Ming YANG
;
Wenbin GUO
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Lupus erythematosus,systemic;
Ventricular function,left
- From:
Chinese Journal of Ultrasonography
2010;19(8):666-669
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis value of the tissue strain imaging in myocardial dysfunction in systemic lupus erythematosus (SLE). Methods Sixty-two patients and sixty controls underwent conventional and tissue Doppler echocardiography. Peak strain and strain rate value during systolic and diastolic phases as well as E/A, left ventricular fraction shortening (LVFS), left ventricular ejection fraction(LVEF) were measured in both SLE and the control groups. Results ①E/A,LVFS and LVEF did not differ between SLE patients and controls( P >0.05). The systolic peak strain and strain rate of SLE patients were lower than those of controls but without significant differences( P >0.05). ②The diastolic peak strain and strain rate of SLE patients were significantly lower than those of controls (P <0.01). ③ The diastolic peak strain and strain rate of antiheart antibody (AHA) positive patients were significantly lower than those of negative ones( P <0.05). Conclusions Strain and strain rate combining with AHA can sensitively detect myocardial dysfunction of SLE.