Effects of sites of fetal spleen cell transplantation on the growth of transplanted tumor and natural killer cells activity in mice
- VernacularTitle:胚胎脾细胞不同移植途径对小鼠接种性肉瘤生长和自然杀伤细胞活性的影响
- Author:
Guoliang WANG
;
Xiaohui MU
;
Guojie WANG
- Publication Type:Journal Article
- Keywords:
Fetal spleen cell/transplantation;
Tumor growth;
Natural killer cell
- From:
Chinese Journal of Organ Transplantation
1997;18(2):96-97
- CountryChina
- Language:Chinese
-
Abstract:
The fetal spleen cells were transplanted following the injection of S180 carcinosarcoma into the muscle,abdominal cavity,peripheral veins and portal vein in mice.The size inhibitory rate of the transplanted tumor and natural killer activity were evaluated 30 and 60 days after the injection.It was found that the growth of transplanted tumor was dramatically inhibited and natural killer activity was increased 30 days after the transplantation.But 60 days after the transplantation only portal venous transplanted tumor showed a satisfactory function of inhibiting tumor growth and natural killer activity maintained at a high level.These results indicated that portal vein was the best approach for the spleen cell transplantation
