Etiology features and risk factors analysis of non-albicans candida infections in hospital
10.3760/cma.j.issn.1008-1372.2010.08.005
- VernacularTitle:医院内非白假丝酵母菌感染的病原学及危险因素研究
- Author:
Wenli FENG
;
Yanqing WANG
;
Jing YANG
;
Zhiqin XI
;
Xiaoqiang JIA
;
Yuan WU
- Publication Type:Journal Article
- Keywords:
Candidiasis/MI/ET;
Risk factors
- From:
Journal of Chinese Physician
2010;12(8):1025-1028
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the etiology features and relevant risk factors of non-albicans candida infections in hospital. Methods 256 patients of non-albicans candida infections admitted in the second hospital of shanxi medical university from April 2006 to March 2008 were enrolled in this investigation, and a prospective case-control study was executed on 256 cases of non-albicans candida infections and 1220 cases of non-fungal infections. The incidence and risk factors of non-albicans candida infections were analyzed by statistical software SPSS13.0. Results Candida glabrata was the most common reason of non - albicans candida infections (38. 28% ) , followed by candida krusei (37. 11% ), candida parapsilosis ( 12. 50% ), candida tropicalis (9. 77% ), candida lusitaniae (2. 34% ). Univariate analysis and multivariate logistic regression analysis showed that aging, length of stay, underlying disease, losing albumin, using prophylaxis antifungal drugs, using broad spectrum antibiotics, invasive examination and treatment ( such as total parenteral nutrition ( TPN ), invasive procedures, central venous catheters, hemodialysis and mechanical ventilation,et al. ) were the independent risk factors for non-albicans candida infections. Conclusions Non-albicans candida was the main of fungal infections in patients. To efficiently control the disease, it will be helpful by early diagnosis and treatment underlying diseases and commodities and using appropriate tools of examine and treatment methods.
