Formation mechanisms, regulating factors and clinical significance of vasculogenic mimicry
10.3760/cma.j.issn.1673-422X.2010.08.006
- VernacularTitle:血管生成拟态的形成机制及其调控因素与临床意义
- Author:
Jie LI
;
Xiaojie MA
;
Bangxian TAN
- Publication Type:Journal Article
- Keywords:
Neovascularization,pathologic;
Neoplasms;
Hypoxia-inducible factor 1;
Vasculogenic mimicry
- From:
Journal of International Oncology
2010;37(8):576-578
- CountryChina
- Language:Chinese
-
Abstract:
Vasculogenic mimicry (VM) can promote tumor growth, invasion, and metastasis. The formation of VM is regulated by various proteins including epithelial cell kinase, phosphoinositide-3 kinase, and hypoxia-inducible factor 1. Local microenvironment also plays an important role in regulating VM formation.
