Antitumor mechanism of FTY720
10.3760/cma.j.issn.1673-422X.2010.07.013
- VernacularTitle:FTY720抗肿瘤机制研究进展
- Author:
Ning ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Signal transduction;
FTY720
- From:
Journal of International Oncology
2010;37(7):520-523
- CountryChina
- Language:Chinese
-
Abstract:
Sphingosine analogue FTY720 exerts good immune suppressive effect by inducing lymphocytes apoptosis and homing, which can be used for organ transplant rejection as well as anti-autoimmune disease treatment. Recent studies have found that FTY720 plays anti-tumor potential by inducing growth arrest and apoptosis as well as inhibiting tumor metastasis.
