The relationship between asthmatic airway epithelial cell and airway remodeling
10.3760/cma.j.issn.1673-4408.2010.05.003
- VernacularTitle:哮喘气道上皮细胞与气道重塑的关系
- Author:
Miao LI
- Publication Type:Journal Article
- Keywords:
Asthma;
Airway epithelial cell
- From:
International Journal of Pediatrics
2010;37(5):450-452
- CountryChina
- Language:Chinese
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Abstract:
The damage of airway epithelial cell in asthma including epithelial cells differentiated into goblet cell, mucous cells metaplasia, which lead to the extracellular matrix increasing, airway walls fibrosis and mucus high secretion. There are many cytokines, growth factors, signal transduction pathways and gene regulating this process.Neuroendocrine cell plays a very important role in the immune adjustment.The repairing process of airway epithelial cells after damaged is a complicated process and affected by many factors.
