Livin and malignant tumor
10.3760/cma.j.issn.1673-422X.2010.07.007
- VernacularTitle:凋亡抑制蛋白Livin与肿瘤
- Author:
Yunlong YU
- Publication Type:Journal Article
- Keywords:
Inhibitor of apoptosis proteins;
Neoplasms;
Livin
- From:
Journal of International Oncology
2010;37(7):501-504
- CountryChina
- Language:Chinese
-
Abstract:
The inhibitor of apoptosis proteins (IAPs) are importants factors of cell apoptosis inhibitors that are closely related to tumorigenesis and tumor development. Livin is selectively expressed in most common human malignant neoplasms. It is demonstrated that Livin may play an important role in tumorigenesis. To research the biological characteristics and the role of Livin is significant to tumor development and progression, chemoresistance ,tumor therapy and prognosis. In recent years,immunotherapy and gene therapy for the targeting of Livin have become a spot research, which provid new strategy and direction for tumor therapy.
