Significance of free-DNA detection to tumor diagnosis
10.3760/cma.j.issn.1673-422X.2010.07.010
- VernacularTitle:游离DNA检测对肿瘤诊断的意义
- Author:
Chenglin LV
;
Wei SHI
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Blood;
DNA
- From:
Journal of International Oncology
2010;37(7):511-514
- CountryChina
- Language:Chinese
-
Abstract:
Free-DNA exists in body fluid of cancer patients, and the concentration is much higher than that of healthy people, and the free DNA is characteristic of tumor issue. This article makes a summary about the study of free DNA in cancer patients,such as methylation,gene mutation, microsatellite instability (MSI) and loss of heterozygosity( LOH ). It has important significance for tumor dignosis,assessment of prognosis and recurrence.
