Iron metabolism and oncogenesis
10.3760/cma.j.issn.1673-422X.2010.08.004
- VernacularTitle:铁代谢与肿瘤生成
- Author:
Zhe CHENG
- Publication Type:Journal Article
- Keywords:
Iron metabolism disorders;
Transferrin;
Receptors,transferrin;
Neoplasms
- From:
Journal of International Oncology
2010;37(8):570-572
- CountryChina
- Language:Chinese
-
Abstract:
Iron metabolism is involved in cancer initiation, progression, metastasis, and angiogenesis.Ferritin,ferritin receptor,transferrin, and transferrin receptor are often overexpressed in cancers. Not only iron deprivation can inhibit the growth of cancers,but also may suppress matrix metalloproteinases-related metastasis.