Antitumor activities of dendritic cells combined with cytokine-induced killer cells
10.3760/cma.j.issn.1673-422X.2010.08.005
- VernacularTitle:树突状细胞联合细胞因子诱导的杀伤细胞抗肿瘤研究进展
- Author:
Chunpeng DOU
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Killer cells;
Neoplasms;
Immunotherapy
- From:
Journal of International Oncology
2010;37(8):573-575
- CountryChina
- Language:Chinese
-
Abstract:
Cytokine-induced killer cells (CIKs) are a kind of non-MHC restricted cytotoxic T cells that have been recognized as the best adoptive immunotherapy against tumor. Dendritic cells(DCs) play a pivotal role in the interaction between tumor cells and T cells. Coculture of CIKs and DCs enhances the proliferation rate and cytotoxicity of CIKs, and has been shown to have strong cancer killing effects in various organ sites.
