Tumor necrosis factor-related apoptosis-inducing ligand and its receptors in lung cancer therapy
10.3760/cma.j.issn.1673-422X.2010.08.013
- VernacularTitle:肿瘤坏死因子相关凋亡诱导配体及其受体与肺癌治疗
- Author:
Xueqiang ZHAO
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
TNF-related apoptosis-inducing ligand;
Apoptosis
- From:
Journal of International Oncology
2010;37(8):597-600
- CountryChina
- Language:Chinese
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Abstract:
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a newly discovered apoptosis-inducing ligand that can induce apoptosis of cancer cells, but not of normal cells, through the activation of multiple signaling transduction pathways. By sensitizing lung cancer cells but not normal cells to apoptosis,TRAIL may become a new strategy for the treatment of lung cancer.
