Immunotherapy of gastric cancer
10.3760/cma.j.issn.1673-422X.2010.08.016
- VernacularTitle:胃癌的免疫治疗
- Author:
Haiyan LIU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Lymphocytes;
Immunotherapy
- From:
Journal of International Oncology
2010;37(8):606-608
- CountryChina
- Language:Chinese
-
Abstract:
The primary immunotherapy for gastric cancer includes cytokine therapy,monoclonal antibody therapy, and cancer vaccines. A lot of researches are being conducted to study gene immunotherapy. It has found that Cbl-b gene plays an important role in regulating anti-tumor immunity and Cbl-b protein is involved in the lymph node metastasis of gastric cancer. Silencing Cbl-b gene in T lymphocytes can enhance anti-tumor immunity,therefore may become an effective treatment for patients with advanced gastric cancer.