Clinical results of intensity modulated radiotherapy for breast cancer after breast-conserving surgery
10.3760/cma.j.issn.1004-4221.2010.05.014
- VernacularTitle:乳腺癌保乳术+化疗后动态调强放疗的临床观察
- Author:
Maimaitiniyazi SIMAYILI
;
Baiketiyaer MUKEDAISI
;
Chunyu HE
;
Xiuqing AI
;
Xianglu ZHU
;
Fang CHENG
;
Suling XU
;
Xinchun ZHANG
;
Musajiang MUNIRE
- Publication Type:Journal Article
- Keywords:
Breast neoplasms/radiotherapy;
Radiotherapy,breast-conserving surgery;
Radiotherapy,intensity modulated;
Prognosis
- From:
Chinese Journal of Radiation Oncology
2010;19(5):434-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the efficacy and cosmetic results of intensity modulate radiation therapy (IMRT) for breast cancer after breast-conserving surgery.Methods From 2003 to 2006, 117 patients with breast cancer, after breast-conserving surgery followed by 4 - 6 cycles of chemotherapy,received intensity modulated radiotherapy (IMRT) or three-dimensional conformal radiotherapy (3DCRT).The radiation dose was 50 Gy in 25 fractions to the whole breast and 10 Gy boost to the tumor bed.Patients with positive hormone receptors then received endocrine treatment.Results The follow-up rate was 94.0% until September 2009.114 and 91 patients were followed up to 3 and 5 years, respectively.The 3-and 5-year overall survival rates were 99.1% and 96%.The 5-year disease free survival and local recurrence rates were 88% and 3.6%.Cosmetic results were satisfied.Severe radiation toxicities, such as radiation pneumonitis, pulmonary fibrosis and heart injury were not found.Conclusions Patients treated with IMRT after breast-conserving surgery have a satisfied prognosis as well as cosmetic results.
