Research on EV71 infection complicated with neurogenic pulmonary edema
10.3760/cma.j.issn.1673-4408.2010.05.008
- VernacularTitle:EV71感染并发神经源性肺水肿的研究现状
- Author:
Xinying ZHANG
- Publication Type:Journal Article
- Keywords:
Neurogenic pulmonary edema;
Enterovirus 71;
Pathogenesis;
Interventions
- From:
International Journal of Pediatrics
2010;37(5):466-469
- CountryChina
- Language:Chinese
-
Abstract:
Enterovirus 71(EV71) infection complicated with neurogenic pulmonary edema (NPE) is an important complication and the main death cause of hand-foot-mouth disease in children. The exact pathogenesis has not yet fully understood. Peripheral sympathetic nervous system hyperexcitability has been recognized, but its central positioning and machanisms are debatable. In recent years, people emphasized the release of cytokines caused by the brainstem injury and/or systemic inflammatory response also plays a very important role in the formation of NPE.The interventions at present are mainly symptomatic treatment in the nervous system involvement, respiratory and circulatory failure. Vaccines are still in the experimental phase of exploration. There is a certain distance from clinical application.
