Advancement and perspective of NF-κB in the research of acute pancreatitis
10.3760/cma.j.issn.1673-4203.2010.09.015
- VernacularTitle:NF-κB在急性胰腺炎治疗研究中的进展及前景
- Author:
Hanzhang ZHU
;
Min XIE
- Publication Type:Journal Article
- Keywords:
Acute pancreatitis;
NF-κB;
Therapy
- From:
International Journal of Surgery
2010;37(9):621-624
- CountryChina
- Language:Chinese
-
Abstract:
Acute pancreatitis is acute inflammation due to autodigestion of pancreatic tissue by trypsogen activation, can induce systemic inflammatory reaction,and deteriorate to be nonfunction and fatality. Nuclear factor kappa B seizes the coral position in the development of acute pancreatitis, regulates gene expression of inflammatory factors and immune protein. This article reviews the therapy of pancreatitis on account of NF-κB.