Detection methods and clinical significance of chimerism after hematopoieticstem cell transplation
10.3760/cma.j.issn.1673-422X.2010.08.023
- VernacularTitle:造血干细胞移植后嵌合体的检测方法及临床意义
- Author:
Jingjing DUAN
;
Liping SU
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplation;
Chimera;
Polymerase chain reaction
- From:
Journal of International Oncology
2010;37(8):626-629
- CountryChina
- Language:Chinese
-
Abstract:
Sequential monitoring of chimerism after hematopoietic stem cell transplantation is important for disease prognosis, improving transplantation success rate, and reducing relapses of the original diseases. The application of molecular genetic markers in combination with quantitative PCR to the assessment of chimerism,in particularly the dynamic quantitative analysis of lineage-specific chimerism, can provide important guidance for clinical practice.
