Microembolic signals and adhesion molecules in patients with cerebral ischemia
10.3760/cma.j.issn.1673-4165.2010.07.010
- VernacularTitle:脑缺血患者的微栓子信号与黏附分子
- Author:
Yanling SUI
;
Xudong PAN
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Intracranial embolism;
Cell adhesion molecules;
Atherosclerosis;
Ultrasonography,Doppler,transcranial
- From:
International Journal of Cerebrovascular Diseases
2010;18(7):527-531
- CountryChina
- Language:Chinese
-
Abstract:
Unstable plaque is one of the major sources of microemboli.The microembolic signals indicate that the patients had unstable plaques and are prone to cerebral infarction recently.A series of adhesion molecules involved in the regulation of inflammatory response and functional changes of cerebral microcirculation during ischemic brain injury.The interaction among the adhesion molecules is conducive to leukocyte adhesion,migration,and platelet aggregation,thereby promoting inflammatory response and thrombosis.Recent studies have indicated that adhesion molecules are closely correlated with the instability of atherosclerotic plaques,which may have involved in the formation process of microemboli.The further study of adhesion molecules and microemboli contributes to implementation of drug intervention.It has a positive significance for the prevention and treatment of cerebral ischemia.
