The role of vascular endothelial growth factor in lung development
10.3760/cma.j.issn.1673-4408.2010.05.005
- VernacularTitle:血管内皮生长因子及其受体与肺发育的研究进展
- Author:
Juanmei WANG
- Publication Type:Journal Article
- Keywords:
Vascular endothelial growth factors;
Lung development;
Hypoxia-inducible factor
- From:
International Journal of Pediatrics
2010;37(5):455-457
- CountryChina
- Language:Chinese
-
Abstract:
Lung development is affected by many factors, and vascular endothelial growth factor is a specially growth factor which has a broad impact on endothelial cell function, it can promote the proliferation and differentiation of cells,as well as promoting angiogenesis and increasing permeability of micro vascular. Further more, it participates in pulmonary vascular development, alveolarization, surfactant synthesis and lung maturity. Thus vascular endothelial growth factor plays an important role in the establishment of normal lung morphology and function, and its abnormal expression may induce abnormal lung development.
