Changes of autonomic nervous function in elderly patients with coronary heart disease accompanying anxiety or depression
10.3760/cma.j.issn.0254-9026.2010.09.007
- VernacularTitle:老年冠心病并存焦虑或抑郁患者自主神经功能的变化
- Author:
Xiongfei ZHANG
;
Xingde LIU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Anxiety;
Depression;
Heart rate
- From:
Chinese Journal of Geriatrics
2010;29(9):725-727
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of autonomic nervous function in elderly patients with coronary heart disease (CHD) accompanying anxiety or depression, and to explore their clinical significance. Methods The 85 elderly inpatients with CHD, diagnosed by selective coronary angiography, were divided into anxiety group (32 cases), depression group (28 cases) and control group (simple CHD without anxiety or depression, 25 cases). The heart rate variability (HRV) was analyzed according to electrocardiograph detected by dynamic cardiograms. Results Compared with the controls, the standard deviation of normal to normal intervals (SDNN), the rate mean square of the differences of successive RR intervals (rMSSD), the percentage of RR intervals differing ＞ 50 ms (PNN50) and the high frequency (HF) decreased markedly in patients with CHD accompanying anxiety or depression, and the low frequency (LF) increased significantly in anxiety group than in control group [(348. 2 ± 70. 6) Hz vs. (295.4+70.0) Hz, t=2.78,P＜0.05], while the HF decreased significantly [(65. 5±14. 4) Hz vs. (77.9± 13. 7) Hz, t=3.16,P＜0. 05]. There were no significant differences between the anxiety group and depression group in the corresponding parameters. Conclusions The injury of vagus nerve function, also autonomic nerve system dysfunction are more seriously in patients with CHD accompanying anxiety or depression than with simple CHD. Actively treating patients with CHD accompanying anxiety or depression may improve their prognosis.
