Current situation, clinical characteristics and management of human swine influenza A H1N1) in children

VernacularTitle:儿童甲型H1N1流感的现状、临床特点及处理
Author: Zhaoyuan QIN ; Lizhi CHEN ; Ling ZHANG
Publication Type:Journal Article
Keywords: Human swine influenza A (H1N1); Children; Clinical characteristics; Management
From: International Journal of Pediatrics 2010;37(5):462-465
CountryChina
Language:Chinese
Abstract: Human swine influenza A (H1N1) is a highly transmissible infectious disease, which has spreaded globally and represented a continuous pandemic threat. The novel virus has predominantly affected the children and young adults. Clinical manifestations generally appear mild, but there are still many patients with severe complications leading to hospitalization. According to the current reports, the mortality in the early stages of the pandemic appears no more than seasonal influenza A . Children (especially less than 5years) are considered to be at higher risk of infection and complications. Pediatric patients with a underlying significant chronic disease such as chronic respiratory disease,cardiovascular disease and immunodeficiency disease, are at a higher risk of death. The neuraminidase inhibitors Oseltamivir and Zanamivir are effective for prophylaxis and treatment. Effective vaccines are regarded to be crucial for the control of influenza pandemics. This review focuses on the epidemiological situation, clinical characteristics and management of human swine influenza A (H1N1), so as to provide practical advice for clinicians.