Long-term results of surgical treatment in 181 cases of advanced stage gallbladder carcinoma
10.3760/cma.j.issn.1007-8118.2010.09.005
- VernacularTitle:181例进展期胆囊癌外科治疗的预后分析
- Author:
Yinghe QIU
;
Chen LIU
;
Bin YI
;
Xiangji LUO
;
Weifeng TAN
;
Qingbao CHENG
;
Yong YU
;
Feiling FENG
;
Xiaoqing JIANG
;
Mengchao WU
- Publication Type:Journal Article
- Keywords:
Gallbladder neoplasms;
Radical resection
- From:
Chinese Journal of Hepatobiliary Surgery
2010;16(9):655-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics and prognostic factors of gallbladder carcinoma and investigate the measures of various modus operandi. Methods The clinicopathological data of 181 patients with advanced gallbladder carcinoma treated in our hospital from June 2002 to June 2008 were retrospectively analyzed. SPSS16. 0 software package was used for statistical analysis.Results The overall median survival rate of the 181 patients with gallbladder carcinoma was 6 months. The median survival rate after radical resection for gallbladder carcinoma was 19.5 months,which was remarkably higher than other R1 resection, R2 resection and palliative operation groups (P ＜0. 01) The RO resection rates were 95.5%, 62. 2%, 14.1% and 4.7%, respectively based on different pathological stages of Nevin( Ⅱ , Ⅲ, Ⅳ, and Ⅴ ). There were significant differences among all groups (P＜0.01). The Cox multivariate analysis revealed that pathological stages of Nevin, total bilirubin, CA-199 and therapeutic method had significantly higher risk ratios for gallbladder carcinoma.Conclusion Radical resection may help to improve the survival rate and prognosis of advanced gallbladder carcinoma.
