Effects of donor antigen treatment and graft venous drainage on pancreas graft survival
- VernacularTitle:供体抗原经门静脉处理及移植物从门静脉回流对大鼠胰腺移植物功能存活的影响
- Author:
Xiaofeng ZHU
;
Jifu WANG
- Publication Type:Journal Article
- Keywords:
Pancreas/transplantation;
Immunology
- From:
Chinese Journal of Organ Transplantation
1997;18(4):204-206
- CountryChina
- Language:Chinese
-
Abstract:
Wistar-to-SD rat pancreas transplantation was performed in 35 SD rat recipients with diabetes-induced.Donor antigen was administered through IV or PV and the antigen treatment was performed before or during the transplantation.Graft vein was drained into IV or PV.The results showed that donor antigen pretreatment via PV combined with graft drainage PV synergistically prolongs the pancreas graft survival,and the effect of simultananeous antigen treat-ment during transplantation is not as satisfactory as that of antigen pretreatment,but may be more practical.