Observation of effect of metformin and exercise therapy for IGT.

VernacularTitle:二甲双胍联合运动疗法对糖耐量减低患者的干预效果
Author: Fengting WEI ; Yinghui GUO ; Jingbo SUN ; Zhixia YANG ; Haichao ZHANG
Publication Type:Journal Article
Keywords: Glucose tolerance test; Exercise therapy; Metformin
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(16):2225-2226
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of metformin and exercise therapy for IGT. Methods 86 patients with IGT were given metformin and exercise therapy,the range of glucose,BMI and symptoms improvement were observed before and after the therapy. Results After 6 months therapy,the fasting blood glucose and 2 h after oral administration of 75 g glucose levels were significantly reduced(P＜0.01＝,BMI reduced(P＜0.05＝.72 cases (83.7%)were back to normal glucose tolerance,14 cases maintained IGT(those unable to adhere to exercise and no diet controlled),0 case became DM. Conclusion Metformin and exercise therapy had good efficacy in curing IGT.