Meta-analysis of clinical effect of prone position ventilation in patients with acute lung injury/acute respiratory distress syndrome
10.3760/cma.j.issn.1672-7088.2010.09.076
- VernacularTitle:俯卧位通气对急性肺损伤和急性呼吸窘迫综合征临床疗效影响的Meta分析
- Author:
Ronghua MA
;
Qing PAN
;
Yun JI
;
Sufei XU
- Publication Type:Journal Article
- Keywords:
Prone position ventilation;
Acute lung injury;
Acute respiratory distress syndrome
- From:
Chinese Journal of Practical Nursing
2010;26(26):71-74
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the short clinical effect of prone position ventilation (PPV) in patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Methods All relative literatures published in the past nine years were searched by computer and hands. Quality appraisal and review data extraction of searched literatures were completed and underwent Meta analysis. Results Eight studies including 184 patients with ALI/ARDS were brought into this Meta-analysis according to the inclusion and the exclusion criteria. Oxygen in artery(PaO2) 、oxygen index (PaO2/FiO2)、pulmonary compliance (C) increased during prone position ventilation, partial pressure of dioxide in artery (PaCO2)、central venous pressure (CVP) 、peak inspiratory pressure ( PIP)、airway resistance (Raw) showed no change, heart rate (HR) and mean artery pressure (MAP) both increased. Conclusions Pulmonary compliance and hypoxemia of patients with ALI/ARDS is improved markedly in PPV. While, due to some limitations of this Meta-analysis, high quality study on PPV is still needed to make clear the clinical effect, mechanism and scientific procedure of PPV and influence of PPV on hemodynamics of patients, so that we can improve the nursing level of patients with ALI/ARDS.
