Influence of enteral nutrition emulsion containing slow-release starch on blood sugar level in patients with craniocerebral injury on bolus feeding: a randomized controlled trial in 120 patients
10.3760/cma.j.issn.1674-635X.2010.04.001
- VernacularTitle:顿服含缓释淀粉的肠内营养乳剂对颅脑损伤患者血糖水平的影响:120例随机对照临床研究
- Author:
Qunfang YIN
;
Jungang XIU
;
Jie LIU
;
Chunyan HUANG
;
Huifen WU
- Publication Type:Journal Article
- Keywords:
Slow-release starch;
Hyperglycemia;
Enteral nutrition;
Craniocerebral injury
- From:
Chinese Journal of Clinical Nutrition
2010;18(4):195-198
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of enteral nutrition (EN) emulsion containing slowrelease starch on blood sugar level in patients with craniocerebral injury. Methods Totally 120 patients with severe craniocerebral injury complicated with hyperglycemia joined this open study and were randomized into control group and study group. Study group was given EN emulsion containing slow-release starch ( Fresubin Diabetes)and control group was given routine EN emulsion ( Fresubin), both for 15 days. Fasting blood glucose (FBG),2-hour postprandial glucose (2hPG), and glycosylated hemoglobin (HbA1c) were examined before EN support and 7 days and 15 days after EN support. Results In the study group, the levels of 2hPG before EN support and on the seventh and fifteenth day after EN support were ( 12.26 ± 2. 36 )mmol/L, (9.76 ± 2.90 ) mmol/L, and (9.78 ± 1.86) mmol/L, respectively. The levels of 2hPG after EN support were both significantly lower than that before EN support (P ＜ 0. 05). However, the levels of FBG and HbA1c in the study group were not significantly different before and after EN support ( P ＞ 0. 05 ). In the control group, the levels of 2hPG on the seventh and fifteenth day after EN support were ( 11.70 ± 2. 80) mmol/L and ( 11.39 ± 2. 44 ) mmol/L, respectively, which were significantly higher than those in study group ( P = 0. 033, P = 0. 020). The levels of FBG and HbA1c werenot significantly different between the study group and the control group ( P ＞ 0. 05 ). Conclusion EN emulsion containing slow-release starch may promote the control of blood sugar in patients with craniocerebral injury complicated with hyperglycemia and improve the level of postprandial blood sugar in those patients.
