Therapeutic observation on the treatment of proteinuria in nephrotic syndrome with Wenshen Xiaobai decoction

VernacularTitle:温肾消白汤治疗肾病综合征蛋白尿的疗效观察
Author: Suting LI
Publication Type:Journal Article
Keywords: Wenshen Xiaobai decoction; Syndrome of Yang deficiency of both spleen and kidney; Proteinuria in nephritic syndrome
From: International Journal of Traditional Chinese Medicine 2010;32(5):419-420
CountryChina
Language:Chinese
Abstract: Objective To observe the effects of Wenshen Xiaoban decoction treating proteinuria in nephrotic syndrome and its adverse reactions. Methods A total of 98 patients with proteinuria who were diagnosed of Yang deficiency of both spleen and kidney by TCM were randomly recruited into a control group (38 patients) and a treatment group (60patients). The treatment group was treated with Wenshen Xiaobai decoction, while the control group was treated with Shenyan Siwei tablets. 24h urine protein, serum albumin (Alb), blood urea nitrogen (BUN), serum creatinine (Scr), and the changes in clinical symptoms were observed before and after the treatment in both groups. Results The treatment group showed better results in 24 hours' urine protein, BUN, Scr, Alb and clinical symptoms than the control group, the difference showing statistical significance(P＜0.05). Conclusion Wenshen Xiaobai decoction can decrease proteinuria and improve renal function and clinical symptoms in NS patients belonging to Yang deficiency of both spleen and kidney.