Analysis of drug-resistant tuberculosis in 296 elderly inpatients in Tianjin
10.3760/cma.j.issn.0254-9026.2010.10.006
- VernacularTitle:天津地区296例老年肺结核住院患者耐药状况分析
- Author:
Qian WU
;
Rong LIU
;
Qi WU
- Publication Type:Journal Article
- Keywords:
Tuberculosis,pulmonary;
Drug resistance;
Elder
- From:
Chinese Journal of Geriatrics
2010;29(10):811-813
- CountryChina
- Language:Chinese
-
Abstract:
Objective To realize the feature of drug resistance in elderly inpatients with tuberculosis in Tianjin. Methods The data of anti-tuberculosis drug sensitivity test of 296 elderly inpatients in Tianjin Haihe Hospital were collected from January 2008 to September 2009. And they were retrospectively analyzed compared with the non-elderly tuberculosis inpatients in the same period.Results (1)The 296 elderly patients with pulmonary tuberculosis were enrolled in this study. The total rate of drug resistance was 28.7% and total rate of multi-drug resistance was 8.8 %. The initial drug resistance rate was 22.2% and initial multi-drug resistance rate was 6.1%. The acquired drug resistance rate was 41.8% and acquired multi-drug resistance rate was 14.3%. (2)The order of drug resistance rate from high to low was isoniazid, streptomycin, rifampin and ethambutal, respectively.(3) The drug resistance rate did not show significant difference among different sex groups (x2 =0. 002, P＞0. 05). (4)The drug resistance rate and multi-drug resistance rate between elderly patients and non-elderly patients had significant differences (x2 = 10.8, 5.24, both P＜0.05). Conclusions The proportion of elderly patients with pulmonary tuberculosis is high, however, its drug resistance rate and multi-drug resistance rate are much lower than non-elderlies.
