Autophagy in gastrointestinal cancers
10.3760/cma.j.issn.1673-422X.2010.09.017
- VernacularTitle:自噬在胃肠道肿瘤的研究
- Author:
Qian LI
- Publication Type:Journal Article
- Keywords:
Autophagy;
Gastrointestinal neoplasms;
Apoptosis
- From:
Journal of International Oncology
2010;37(9):695-696
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a lysosome-mediated degradation process that takes part in maintaining cell stability. In the early stage of gastrointestinal tumors, autophagy removes toxic injuries to protect against tumor progression, while in the progressive stage, autophagy also exhibits a cytotoxic effect. Autophagy and apoptosis act in both antagonistic and synergistic fashion. Manipulation of autophagy may be a new method to prevent or treat gastrointestinal tumors.
