Early biomarkers for acute kidney injury
10.3760/cma.j.issn.1673-4912.2010.05.031
- VernacularTitle:早期诊断急性肾损伤的生物学标志物研究现状
- Author:
Ling HOU
- Publication Type:Journal Article
- Keywords:
Acute kidney injury;
Acute renal failure;
Biomarker;
IL-18;
Kidney injury molecule-1;
Liver-type fatty acid binding protein;
Nephrotoxicity;
Neutrophil gelatinase-associated lipocalin
- From:
Chinese Pediatric Emergency Medicine
2010;17(5):454-456
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury (AKI) represents a common and devastating problem in clinical medicine. The lack of early biomarkers for AKI has led to a delay in initiating potentially effective therapies.Identification of novel biomarkers for AKI has progressed to the clinical phase of the biomarker discovery process. The most promising AKI biomarkers include neutrophil gelatinase-associated lipocalin, IL-18, kidney injury molecule-1 and liver-type fatty acid binding protein. In this article, we review the study of neutrophil gelatinase-associated lipocalin,IL-18, kidney injury molecule-1 and liver-type fatty acid binding protein in recent years,in order to provide the theory basis for the clinical application of the early biomarkers for AKI.
