A Case of Primary Duodenal Carcinoid Tumor.
- Author:
Joon Sang LEE
1
;
Jong Hoon YOO
;
Jeong Seok LEE
;
Eui Hyuk CHOI
;
Dong Yun LEE
;
Soo Hee HONG
;
Hyung Joo KWON
;
Moo Yeol LEE
;
Young Woo PARK
;
Cheol Ho LEE
;
Young Mug KIM
;
Soon Chul HWANG
Author Information
1. Department of Internal Medicine, Wallace Memorial Baptist Hospital, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Carcinoid tumor;
Duodenum
- MeSH:
Aged;
Biopsy;
Carcinoid Tumor*;
Chromogranin A;
Coloring Agents;
Diagnosis;
Duodenum;
Enterochromaffin Cells;
Female;
Humans;
Incidence;
Melena;
Neoplasm Metastasis;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
1999;19(2):275-280
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinoid tumors are slow growing, rare neoplasms that arise from enterochromaffin cells, with malignant potential. Primary duodenal carcinoid tumors are rare, the reported incidence being 2.0 ~8.9% of all gastrointestinal carcinoid tumors. Unless the carcinoid syndrome has developed, the non-specificity of the symptoms and physical findings, makes the clinical diagnosis of these tumors difficult. However, with the introduction of large and deep endoscopic biopsies, it is possible to diagnose duodenal carcinoid tumors at an early stage. Usually, local resection is the therapy of choice because of the very slow growth of the lesion and the low incidence of metastasis. Radical surgery is mandatory only in lesions more than 2 cm in diameter, or in the presence of muscular invasion. A 69-year-old female visited our medical department, having had symptoms of upper ab-dominal pain and intermittent melena for 1 week. Endoscopic examination showed 2.5 2.5 cm sized elevated mass lesion with central ulceration in the anterior wall side of the duodenal bulb. Immunohistochemical stains of the biopsy specimen showed that the tumor cells are positive reactivity for NSE (neuron-specific-enolase), chromogranin A, and cyto-keratin.
