Determinants of arterial distensibility in middle-age and elderly patients on the treatment of hemodialysis
10.3760/cma.j.issn.1671-0282.2010.10.018
- VernacularTitle:中老年血液透析患者颈总动脉僵硬度的影响因素
- Author:
Hongqi REN
;
Yan LI
;
Qing CAI
;
Shujing HAN
;
Meiyue LV
;
Ling LI
- Publication Type:Journal Article
- Keywords:
End-stage renal disease;
Arterial stiffness;
Hemodialysis;
Gardio vascular disease;
Determinant
- From:
Chinese Journal of Emergency Medicine
2010;19(10):1070-1073
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate arterial stiffness in middle-age and elderly patients on the treatment of hemodialysis and to investigate the risk factors of arterial stiffness. Method A total of 87 in middle-age and elderly patients on the treatment of hemodialysis were enrolled. The distensibility coefficient (DC) of the common carotid artery was evaluated by an ultrasonic phase-locked echo-tracking system. Serum albumin, total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), glucose, creatinine,calcium, phosphorus, and intact parathyroid hormone (iPTH) were determined with well established methods. Results The ages of 87 patients ranged from 45 to 81 years, and the duration of treatment with hemodialysis was varied from 3 to 204 months . The carotid DC was ( 13.39 ± 5.32 ) × 10-3/kPa in middle-age and elderly patients on hemodialysis. In stepwise multiple regression analysis, systolic blood pressure (β = -0.349, P ＜ 0.001), age (β=-0.323, P ＜ 0.001), diabetes (β =-0.195,P = 0.027), and serum calcium (β =-0.276,P =0.002) were independently correlated with carotid DC. Conclusions Systolic blood pressure, age, diabetic,serum calcium were independent determinants for arterial stiffness of carotid artery in middle-age and elderly patients on hemodialysis.
