Concurrent versus sequential adjuvant radio-chemotherapy after mastectomy for breast cancer: a Meta-analysis
10.3760/cma.j.issn.1671-7368.2010.10.023
- VernacularTitle:乳腺癌术后辅助治疗中同步与序贯放化疗疗效的荟萃分析
- Author:
Qing MA
;
Yali LIU
;
Zhongqing ZHENG
;
Yaoyao REN
;
Kehu YANG
;
Li MA
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Meta-analysis
- From:
Chinese Journal of General Practitioners
2010;09(10):723-725
- CountryChina
- Language:Chinese
-
Abstract:
With computer and manual search of literatures on the comparison of concurrent with sequential adjuvant radio-chemotherapy after mastectomy for breast cancer, 4 eligible randomized controlled trials were found; the RevMan 5.0 software was used for Meta-analysis. The results showed that concurrent radio-chemotherapy reduced local recurrence more prominently than sequential radio-chemotherapy in patients with positive axillary lymph nodes( P = 0. 003 ). However, differences in 5-year overall survival,5-year disease-free survival and metastasis-free survival between two groups were not significant (P =0. 670,P =0. 200, P =0. 350).
