Pyoderma Gangrenosum in Ulcerative Colitis.
- Author:
Jun Ho SEOK
1
;
Jin Chul PARK
;
Soon Wook KWUN
;
Jin Soo CHOI
;
Jun Hwan KIM
;
Yeung Sung KIM
;
Tae Nyun KIM
;
Mun Kwan CHUNG
Author Information
1. Department of Internal Medicine, College of Medicine, Yeungnam University, Taegu, Korea.
- Publication Type:Original Article
- Keywords:
Ulcerative colitis;
Pyoderma gangrenosum;
Steroid
- MeSH:
Abdominal Pain;
Adrenal Cortex Hormones;
Anti-Bacterial Agents;
Colitis;
Colitis, Ulcerative*;
Colon;
Cromolyn Sodium;
Cyclosporine;
Dapsone;
Diagnosis;
Diarrhea;
Hemorrhage;
Humans;
Mucus;
Pyoderma Gangrenosum*;
Pyoderma*;
Rectum;
Skin Diseases;
Ulcer*
- From:Korean Journal of Gastrointestinal Endoscopy
1999;19(2):300-305
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ulcerative colitis is an inflammatory disorder that affects the rectum and extends proximally to affect a variable extent of the colon. The major symptoms of ulcerative colitis include diarrhea, rectal bleeding, the passage of mucus, and abdominal pain. Ulcer-ative colitis also may be complicated by many local and systemic disorders as extrain-testinal manifestations. Pyoderma gangrenosum is the most severe dermatologic com-plication associated with ulcerative colitis. It is a painful , chronic, ulcerating skin disease of unknown cause. Diagnosis is clinical, there being no accepted histological diagnostic criteria. Conventional therapy is empirical, usually with high dose corticosteroids, but var-ious other agents have been tried with occasional success including topical antibiotics, cyclosporine, disodium cromoglycate, and dapsone. This patient was treated with high dose corticosteroid (prednisolone 1 mg/kg/day) and discharged with clinical improvement. So we report this case with a literature review.
