Study on inhibition of anthraquinone in Polygonum Cillinerve (Nakai) Ohwi to Nitrosation
10.3760/cma.j.issn.1673-4246.2010.04.043
- VernacularTitle:朱砂七总蒽醌抑制亚硝化反应的研究
- Author:
Xiaomei WANG
;
Jian LI
;
Jinbao GUO
- Publication Type:Journal Article
- Keywords:
Polygonum Cillinerve (Nakai) Ohwi;
Anthraquinone;
Sodium nitrite;
Nitrosamine
- From:
International Journal of Traditional Chinese Medicine
2010;32(4):355-356
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study inhibitory activity of anthraquinone in Polygonum Cillinerve(Nakai) Ohwi (anthraquinone in PCO) to nitrosation. Methods Anthraquinone was extracted from Polygonum Cillinerve(Nakai) Ohwi with sulfuric acid and chloroform as solvents. The capability of scavenging sodium nitrite and disconnecting nitrosamine synthesis with anthraquinone in PCO were determined by spectrophotometry under simulated human gastric juice. Results Both the sodium nitrite scavenging rate and the nitrosamine synthesis disconnecting rate showed the positive correlation with the concentration of anthraquinone in PCO. The strongest capability of scavenging sodium nitrite was 53.5%, and the strongest capability of disconnecting nitrosamine synthesis was 71.3%. Conclusion Anthraquinone in PCO had strong capability of scavenging sodium nitrite and disconnecting nitrosamine synthesis.
