Clinical analysis on 36 cases of sub-acute infective endocarditis
10.3760/cma.j.issn.1008-6315.2010.07.008
- VernacularTitle:亚急性感染性心内膜炎36例临床分析
- Author:
Xiaoru ZENG
;
Changgeng FANG
;
Qing ZHOU
- Publication Type:Journal Article
- Keywords:
Sub-acute infective endocarditis;
Clinical characteristics;
Pathogenic bacteria
- From:
Clinical Medicine of China
2010;26(7):696-698
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the basic pathogenic cause,clinical characteristics,treatment methods and prognosis of sub-acute infective endocarditis (IE) ,and to improve the diagnosis and treatment against it Methods The basic cardiac disease,clinical characteristics,pathogenic bacteria,ultrasound cardiogram, therapy and prognosis of 36 cases of sub-acute IE was retrospectively analyzed. Results Compared to previous reports, the proportion of rheumatic cardiac disease was a little lower, whereas the proportion of congenital cardiac disease and not-recorded cardiac diseases were a little higher.The main clinical characteristics showed as fever, heart failure, increasing in number of neutrophile granulocyte,blood sedimentation and anemia, The positive rate of blood culture was 58. 33% with the most common pathogenic bacterium of streptococcus viridans. Endocardial vegetation has been diagnosed in 63. 89% of patients through-thoracic echo-cardiography. The short-term fatality rate was 19. 44% . Conclusions There have been significant changes in the basic pathogenic causes,clinical characteristics and pathogenic bacteria of sub-acute IE as compared to the previous reports. The fatality rate remains high even after active treatment. Early surgical operation is recommended to those suitable patients.
