The roles of netrin-1 and its receptors in brain ischemia
10.3760/cma.j.issn.1673-4165.2010.08.013
- VernacularTitle:Netrin-1及其受体在脑缺血中的作用
- Author:
Qiong GONG
;
Jian YU
- Publication Type:Journal Article
- Keywords:
Netrin-1;
Netrin receptors;
Nerve growth factors;
Brain ischemia;
Apoptosis
- From:International Journal of Cerebrovascular Diseases
2010;18(8):637-640
- CountryChina
- Language:Chinese
-
Abstract:
The netrin family represented by netrin-1 is currently one of the most concerned axon guidance factors. Netrin-1 plays guidance roles for axon growth and cell migration by the dual mechanisms of attracting/excluding during the embryonic development. At the same time, netrin-1 also widely expresses in the adult nervous system and involves in the reconstruction of the structure and function after the achft nervous system injury. This article reviews the roles of netrin-1 in ischemic brain injury.
