Aberrant methylation of tumor suppressor genes in salivary adenoid cystic carcinoma
10.3760/cma.j.issn.1673-422X.2010.09.011
- VernacularTitle:抑癌基因甲基化与涎腺腺样囊性癌
- Author:
Chuanming ZHENG
- Publication Type:Journal Article
- Keywords:
Methylation;
Tumor suppressor genes;
Carcinoma,adenoid cystic;
Salivary glands
- From:
Journal of International Oncology
2010;37(9):676-679
- CountryChina
- Language:Chinese
-
Abstract:
Methylation of tumor suppressor gene(TSG), currently a hot field in cancer research, is involved in many biological processes including cell cycle regulation, cell signal transduction, DNA apoptosis,tumor invasion and metastasis. The level of TSG methylation is significantly associated with the development of salivary adenoid cystic carcinoma and its biologic behavior.
