Effectiveness of aspirin in preventing peripherally inserted central venous catheter-related thrombosis

VernacularTitle:阿司匹林对经外周静脉置入中心静脉导管相关性血栓的预防作用
Author: Xuying LI ; Zhenqiu SUN ; Yongyi CHEN ; Jinhua LI ; Zhong YUAN ; Yuhua WANG
Publication Type:Journal Article
Keywords: Aspirin; Peripherally inserted central venous catheter; Thrombosis; Phlebitis
From: Chinese Journal of Clinical Nutrition 2010;18(2):121-123
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effectiveness of aspirin in preventing peripherally inserted central venous catheter (PICC) -related thrombosis. Methods Totally 360 cancer patients who had undergone routine PICC placement were equally randomized into aspirin group (receiving conventional PICC maintenance plus oral administration of aspirin; 100 mg/d, for consecutively 21 days) and control group (conventional PICC catheter maintenance). The incidences of phlebitis and thrombosis were observed in both two groups. Results The incidences of phlebitis and thrombosis were 3.3% and 0 in aspirin group, which were significantly lower than those in control group (8.9% , P = 0. 025; 1.7% , P = 0. 025). Conclusion The oral administration of aspirin after the PICC placement can reduce PICC-related thrombosis and phlebitis.