Unexplained rhabdomyolysis: clinical analysis of twenty three cases
10.3760/cma.j.issn.1671-0282.2010.10.015
- VernacularTitle:群发性横纹肌溶解症23例临床分析
- Author:
Xufeng CHEN
;
Peipei HUANG
;
Jian KANG
;
Kai SUN
;
Jinsong ZHANG
- Publication Type:Journal Article
- Keywords:
Rhabdomyolysis;
Haff disease;
Red swamp crayfish;
Diagnosis;
Complication;
Acute renal failure;
Blood purification;
Treatment
- From:
Chinese Journal of Emergency Medicine
2010;19(10):1062-1065
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate clinical features, therapeutic regimen and prognosis of unexplained rhabdomyolysis. Method Clinical manifestations, therapeutic regimen and prognosis were recorded in 23 patients,who were admitted to The First Affiliated Hospital of Nanjing Medical University 13 to 27 August,2010.The 23 patients were diagnozed as unexplained rhabdomyolysis. Results The patients all presented myalgia of upper body,like neck,waist and back,maybe with asthenia, nausea,dyspnea,abdominal pain, red urine or changed color of urine. Laboratory examination: obviously step-up of creatine kinase [CK: (4655 ± 2556) U/L( normal: 25 ～ 190U/L) AST:(141 ±78) U/L(normal:10～45 U/L),LDH:(348± 127) U/L(normal: 110～ 250 U/L)]and myoglobin[( Mb ＞ 1000 μg/L (normal: 0 ～ 50 μg/L)]. Therapeutic regimen included treatment of the underlying diseases, volume repletion, alkalization and dealing with the complications. No patients developed acute renal failure.All the patients recovered. Conclusions Rhabdomyolysis is a syndrome with different clinical manifestations.However, early diagnosis, proper treatment could prevent serious complications,and prognosis is good.
