Infiltrate and deposition of Ig in the graft
- VernacularTitle:肝移植大鼠移植肝内浸润细胞和免疫球蛋白的变化
- Author:
Junhong SUN
;
Mongchao WU
;
Han CHEN
- Publication Type:Journal Article
- Keywords:
Transplantation;
Tolerance;
Immunohistochemistry
- From:
Chinese Journal of Organ Transplantation
1996;17(3):131-133
- CountryChina
- Language:Chinese
-
Abstract:
We investigated the mechanism of tolerance induction by identifying differences in infiltrating cell population and Ig subclasses deposition between tolerant and rejecting rat liver allografts.There were occasional minor differences in the T cell or CD11 b/c+(monoeyte/macrophage/granulocyte)infiltrate.By contrast,there was a major difference in B cell infiltrate with more B cells in tolerant grafts.IgM was increased in both tolerant and rejecting livers while deposition of IgG1 was observed in rejecting but not in tolerant livers.
