Efflux pumps in multidrug resistant Escherichia coli
10.3760/cma.j.issn.1674-2397.2010.05.011
- VernacularTitle:多药耐药大肠埃希菌抗菌制剂外排泵基因研究
- Author:
Weihua WANG
;
Li WANG
;
Wanfei Lü
;
Jie CHEN
;
Yuanyuan ZHANG
;
Xiongying MAO
;
Hui CHEN
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Efflux pumps;
Multidrug resistant;
Gene
- From:
Chinese Journal of Clinical Infectious Diseases
2010;03(5):290-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prevalence of 11 efflux pumps in isolates of multidrugresistant Escherichia coli(MDR-ECO). Methods Efflux pumps emrB, emrD , emrE, mdfA, sugE, mdtl,tehA, oqxA, qacE△1, qacE and smr-2 were detected by polymerase chain reaction(PCR)in 20 MDR-ECOs isolated from clinical samples. Results Efflux pumps emrB, emrD, emrE, mdfA, sugE, mdtI, qacE △1, tehA and oqxA were detected, and 8 efflux pumps were found in the same strain. Conclusion Multidrug- resistance in Escherichia coli may be related with efflux pumps.
